Publications
2024
Boff JM, Shrestha AP, Madireddy S, Viswaprakash N, Della Santina L, Vaithianathan T. The Interplay between Neurotransmitters and Calcium Dynamics in Retinal Synapses during Development, Health, and Disease. Int. J. Mol. Sci. 2024 Feb 13; 25(4):2226. doi: 10.3390/ijms25042226.
Shrestha AP, Stiles M, Grambergs RC, Boff JM, Madireddy S, Mondal K, Rajmanna R, Porter H, Sherry DM, Proia RL, Vaithianathan T, Mandal N. The Role of Sphingosine-1-Phosphate Receptor 2 in Mouse Retina Light Responses. Biomolecules. 2023 Nov 23; 13(12):1691. doi: 10.3390/biom13121691.
Shrestha AP, Rameshkumar N, Boff JM, Rajmanna R, Chandrasegaran T, Frederick CE, Zenisek D, Vaithianathan T. The Effects of Aging on Rod Bipolar Cell Ribbon Synapses. Cells. 2023 Sep 29; 12(19):2385. doi: 10.3390/cells12192385.
Lenin R, Jha KA, Gentry J, Shrestha A, Culp EV, Vaithianathan T, Gangaraju R. Tauroursodeoxycholic Acid Alleviates Endoplasmic Reticulum Stress-Mediated Visual Deficits in Diabetic tie2-TNF Transgenic Mice via TGR5 Signaling. J Ocul Pharmacol Ther. 2023 Mar;39(2):159-174. doi: 10.1089/jop.2022.0117. Epub 2023 Feb 15. PMID: 36791327; PMCID: PMC10081728.
Vaithianathan T, Schneider EH, Bukiya AN, Dopico AM. Cholesterol and PIP2 Modulation of BKCA Channels. Advances in Experimental Medicine and Biology. 1422, 217-243. doi.org/10.1007/978-3-031-21547-6_8
2023
2022
Shrestha AP, Vaithianathan T. Tracking the dynamics of single fused synaptic vesicle proteins from a single ribbon active zone in zebrafish retinal bipolar cells. STAR Protoc. 2022 Jan 20;3(1):101107. doi: 10.1016/j.xpro.2021.101107. PMID: 35098163; PMCID: PMC8783205.
Shrestha AP, Saravanakumar A, Konadu B, Madireddy S, Gibert Y, Vaithianathan T. Embryonic Hyperglycemia Delays the Development of Retinal Synapses in a Zebrafish Model. Int J Mol Sci. 2022 Aug 26;23(17):9693. doi: 10.3390/ijms23179693. PMID: 36077087; PMCID: PMC9456524.
Vaithianathan T, Wollmuth LP, Henry D, Zenisek D, Matthews G. Tracking Newly Released Synaptic Vesicle Proteins at Ribbon Active Zones. iScience. 2019 Jul 26;17:10-23. doi: 10.1016/j.isci.2019.06.015. Epub 2019 Jun 13. PMID: 31247447; PMCID: PMC6598641.
2019
Vaithianathan T, Henry D, Akmentin W, Matthews G. Nanoscale dynamics of synaptic vesicle trafficking and fusion at the presynaptic active zone. Elife. 2016 Feb 11;5:e13245. doi: 10.7554/eLife.13245. PMID: 26880547; PMCID: PMC4786419.
2016
Vaithianathan T, Henry D, Akmentin W, Matthews G. Functional roles of complexin in neurotransmitter release at ribbon synapses of mouse retinal bipolar neurons. J Neurosci. 2015 Mar 4;35(9):4065-70. doi: 10.1523/JNEUROSCI.2703-14.2015. PMID: 25740533; PMCID: PMC4348196.
Viswaprakash N, Vaithianathan T, Viswaprakash A, Judd R, Parameshwaran K, Suppiramaniam V. Insulin treatment restores glutamate (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor function in the hippocampus of diabetic rats. J Neurosci Res. 2015 Sep;93(9):1442-50. doi: 10.1002/jnr.23589. Epub 2015 Mar 24. PMID: 25807926.
2015
2014
Vaithianathan T, Matthews G. Visualizing synaptic vesicle turnover and pool refilling driven by calcium nanodomains at presynaptic active zones of ribbon synapses. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8655-60. doi: 10.1073/pnas.1323962111. Epub 2014 May 27. PMID: 24912160; PMCID: PMC4060678.
2013
Vaithianathan T, Akmentin W, Henry D, Matthews G. The ribbon-associated protein C-terminal-binding protein 1 is not essential for the structure and function of retinal ribbon synapses. Mol Vis. 2013 Apr 18;19:917-26. PMID: 23687428; PMCID: PMC3654860.
Vaithianathan T, Zanazzi G, Henry D, Akmentin W, Matthews G. Stabilization of spontaneous neurotransmitter release at ribbon synapses by ribbon-specific subtypes of complexin. J Neurosci. 2013 May 8;33(19):8216-26. doi: 10.1523/JNEUROSCI.1280-12.2013. PMID: 23658160; PMCID: PMC3694337.
Kanju PM, Parameshwaran K, Vaithianathan T, Sims CM, Huggins K, Bendiske J, Ryzhikov S, Bahr BA, Suppiramaniam V. Lysosomal dysfunction produces distinct alterations in synaptic alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid and N-methyl-D-aspartate receptor currents in hippocampus. J Neuropathol Exp Neurol. 2007 Sep;66(9):779-88. doi: 10.1097/nen.0b013e3181461ae7. PMID: 17805008.
Wijayawardhane N, Shonesy BC, Vaglenova J, Vaithianathan T, Carpenter M, Breese CR, Dityatev A, Suppiramaniam V. Postnatal aniracetam treatment improves prenatal ethanol induced attenuation of AMPA receptor-mediated synaptic transmission. Neurobiol Dis. 2007 Jun;26(3):696-706. doi: 10.1016/j.nbd.2007.03.009. Epub 2007 Mar 30. PMID: 17493826.
Parameshwaran K, Sims C, Kanju P, Vaithianathan T, Shonesy BC, Dhanasekaran M, Bahr BA, Suppiramaniam V. Amyloid beta-peptide Abeta(1-42) but not Abeta(1-40) attenuates synaptic AMPA receptor function. Synapse. 2007 Jun;61(6):367-74. doi: 10.1002/syn.20386. PMID: 17372971.
Wijayawardhane N, Shonesy BC, Vaithianathan T, Pandiella N, Vaglenova J, Breese CR, Dityatev A, Suppiramaniam V. Ameliorating effects of preadolescent aniracetam treatment on prenatal ethanol-induced impairment in AMPA receptor activity. Neurobiol Dis. 2008 Jan;29(1):81-91. doi: 10.1016/j.nbd.2007.08.001. Epub 2007 Aug 14. PMID: 17916430.
Vaglenova J, Pandiella N, Wijayawardhane N, Vaithianathan T, Birru S, Breese C, Suppiramaniam V, Randal C. Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. Neuropsychopharmacology. 2008 Apr;33(5):1071-83. doi: 10.1038/sj.npp.1301496. Epub 2007 Jul 4. PMID: 17609677.
2008
2007
2006
Suppiramaniam V, Vaithianathan T, Parameshwaran K. Electrophysiological analysis of interactions between carbohydrates and transmitter receptors reconstituted in lipid bilayers. Methods Enzymol. 2006;417:80-90. doi: 10.1016/S0076-6879(06)17007-X. PMID: 17132499.
2005
Vaithianathan T, Manivannan K, Kleene R, Bahr BA, Dey MP, Dityatev A, Suppiramaniam V. Single channel recordings from synaptosomal AMPA receptors. Cell Biochem Biophys. 2005;42(1):75-85. doi: 10.1385/CBB:42:1:075. PMID: 15673930.
Vaithianathan T, Matthias K, Bahr B, Schachner M, Suppiramaniam V, Dityatev A, Steinhaüser C. Neural cell adhesion molecule-associated polysialic acid potentiates alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor currents. J Biol Chem. 2004 Nov 12;279(46):47975-84. doi: 10.1074/jbc.M407138200. Epub 2004 Aug 17. PMID: 15317811.
Chicoine LM, Suppiramaniam V, Vaithianathan T, Gianutsos G, Bahr BA. Sulfate- and size-dependent polysaccharide modulation of AMPA receptor properties. J Neurosci Res. 2004 Feb 1;75(3):408-16. doi: 10.1002/jnr.10871. PMID: 14743454.